Tuesday Nov.10, 2020

💉 Pfizer's COVID-19 vaccine breakthrough

_McDonald's = the Regina George of fast food_
_McDonald's = the Regina George of fast food_

Hey Snackers,

In the whirlwind of last week, you probably missed this: "Britain's new polar ship 'Boaty McBoatface' heads for open seas." That's what you get when you ask the internet for name recs.

Markets rallied yesterday on promising vaccine news. But the techy Nasdaq index fell because "pandemic winners" like Zoom could lose on reopening.

Vax

Pfizer and BioNTech say their COVID-19 vaccine is more than 90% effective (whoa)

Biggest vax flex yet... Big pharma Pfizer and German biotech BioNTech said their jointly developed COVID-19 vaccine was more than 90% effective in Phase 3 trials — that's huge. For reference:

  • 50% to 60% effectiveness: Dr. Fauci has said this rate would be acceptable to approve a vaccine (the flu vaccine is only 40% to 60% effective).
  • 60% to 70%: Health experts say this rating would be a big win. Pfizer's 90%+ would be a wild success — but results are preliminary and haven't been peer-reviewed.

Please get it mRN-ASAP... If Pfizer's vax gets FDA-approval, it would be the 1st mRNA vaccine ever approved for human use. Unlike OG vaccines (which use a weakened virus to generate an immune response), mRNA ones teach cells to destroy the virus.

  • Moderna stock popped too because it's also in final stage trials of an mRNA vaccine. AstraZeneca, which is in final trials for a traditional vax, dropped.
  • Reopening stocks majorly soared: AMC was up 51%, Carnival was up 39%, and Delta spiked 17%. "Pandemic Winners" like Netflix, Peloton, and Zoom all dropped big.
  • BTW: Vaccines usually take around 10 years from development to approval. This vax is on pace for a record-shattering timeframe.

Pfizer has a big leg up... if others have to compete with a 90% efficacy rate — that's highly attractive to vax-buying countries, even though Pfizer's vax comes with more rollout challenges. Moderna seems the most likely to get similar results (because: #mRNAlife). Pfizer's planning to request FDA emergency use authorization in late November. With approval, Pfizer says it can make 50M doses in 2020 and 1.3B in 2021.

Awk

McDonald's drops "the McPlant" on the same day that Beyond face plants

Well, this is awkward... or is it just savage? Yesterday, plant-based icon Beyond Meat served up a surprising loss and disappointing quarterly sales. On the same day, McDonald's delivered expectation-beating growth and unleashed this on the world: "the McPlant."

  • The McPlant is a (wait for it) plant-based burger crafted "for McDonald’s, by McDonald’s." Mickey D’s plans to test it in several countries next year.
  • Beyond Meat says it co-created the McPlant patty, but McDonald's made zero mention of Beyond in its announcement. Awkward...

Not feelin' McLovin'... Beyond might be feeling a bit used. Last year, McDonald’s began testing a meatless burger ("PLT") in Canada that used Beyond patties. While McDonald's ended that pilot, it clearly saw potential in the meatless, McPlant-based market. Mickey D’s hasn't yet confirmed the supplier, but it won't be making it itself.

McDonald's wants all the attention... If Beyond is supplying, that could mean a lucrative long-term partnership with America's largest restaurant by sales — would be nice, considering Beyond lost $19M last quarter. But McDonald's clearly isn't showcasing Beyond's brand with McPlant — unlike Dunkin' with the Beyond Breakfast sandwich. Beyond might be willing to go anonymous and trade brand recognition for cash recognition.

Beanie

Supreme gets bought for $2.1B by Vans-owner VF Corp

Soulless name... soulful brand. VF Corp is the unfortunately-named company which owns Vans, North Face, Dickies, and soon... Supreme. The popular streetwear/skater brand is best known for its iconic red logo that appears everywhere. Now:

  • Supreme is getting bought for $2.1B and will become part of VF's publicly-traded stock. It's VF's largest acquisition since it snatched up Timberland in 2011 for $2.3B.
  • VF stock jumped as much as 17% yesterday on the news — the most in over 30 years. But it's still down over 20% this year.

Googling "how to be cool"... Slap a Supreme sticker on it. Supreme reeks with "cool factor" — that's something VF needs badly, since most of its brands are past their early 2000s Avril Lavigne peak. Vans and Timbs sales are slowing, and VF has already sold off some of its "declining cool" and industrial workwear brands: Wrangler, Lee, and 7 For All Mankind.

This is a learn-cquisition... Supreme is a master at generating hype, with everything from weekly product releases to buzzy collabs — VF wants to learn its ways. It'll also leverage Supreme's digital strategy and social media prowess to expand its ecommerce channels (#linkinbio). But Supreme's biggest appeal is scarcity. If VF scales it up too much, it might lose that "special" factor — then they'd both lose.

What else we’re Snackin’

  • Channel5: Netflix tests its first traditional channel offering in France to reduce the choice paralysis of picking a show.
  • Future: Two people finished the 1st-ever ride in a Virgin Hyperloop tube. It's like a subway pod shooting super fast through a tube.
  • High: Aurora Cannabis shares surged on better-than-expected sales and the Biden win. Investors are hoping for pro-pot reform.
  • Trucked: Electric truck-maker Nikola lost $118M last quarter, compared to $16M in the same quarter last year.
  • Meds: Biogen stock plunged nearly 30% after an FDA panel voted against its experimental Alzheimer's treatment.
  • Jet: United Airlines boosts its Thanksgiving flight schedule as it expects the most travelers since March.

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Tuesday

Disclosure: Authors of this Snacks own shares of Apple and Moderna

ID: 1405942

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Tesla had a good ride, but the stock’s price destruction is historic

Few people have created as much value as Elon Musk. The iconoclastic entrepreneur took Tesla from a market capitalization of roughly $2 billion at the time of its IPO in 2010 to $1.2 trillion in early 2023. That’s a return of about 55,000%. Musk made a lot of people a lot of money.

On the other hand, Tesla shares are down nearly 60% since their all-time peak. The company has ceded ground in EVs, prompting a series of profit crushing price cuts to preserve market share. The cumulative loss in market value over that period is pushing $800 billion. Few corporate executives have presided over such a degree of value destruction.

And it could get worse, as people are bracing for an ugly update when Tesla reports after the close Tuesday.

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Smaller AI models are in

Tech companies that have long touted the enormity of their AI models are now saying size doesn’t always matter.

Microsoft is the latest tech company to introduce smaller AI models, as part of its Phi-3 tech family. Last week Meta released two smaller models of its AI Llama 3 and earlier this year Alphabet did the same. All are open sourcing these models to encourage wider adoption.

Microsoft says its smallest model, which can fit on a smartphone and wouldn’t need to be connected to the internet to work, is nearly as good as OpenAI’s GPT-3.5. A Microsoft exec suggested this less expensive model could be a good fit for online advertisers, if not doctors.

Microsoft says its smallest model, which can fit on a smartphone and wouldn’t need to be connected to the internet to work, is nearly as good as OpenAI’s GPT-3.5. A Microsoft exec suggested this less expensive model could be a good fit for online advertisers, if not doctors.

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Adding fuel to the fee fire was the launch of Runes, a new protocol that lets developers create memecoins on top of the bitcoin blockchain. The debut was so popular that fees popped as traders fought for limited block space.

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Stock market gains for 2024 cut by more than half

All of the sudden, the stock market seems to be running out of steam.

There’s no big mystery here. War in the Mideast has pushed up oil prices, which will help keep inflation elevated. And annoyingly high price increases in March have already pushed the June Fed rate cuts the market was banking on farther into the uncertain future.

All that’s added up to higher interest rates and lower stock prices.

Tech
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AI needs so much electricity that tech companies are getting into the energy business

To accommodate tech companies’ pivots to artificial intelligence, tech companies are increasingly investing in ways to power AI’s immense electricity needs.

Most recently, OpenAI CEO Sam Altman invested in Exowatt, a company using solar power to feed data centers, according to the Wall Street Journal.

That’s on the heals of OpenAI partner, Microsoft, working on getting approval for nuclear energy to help power its AI operations. Last year Amazon, which is a major investor in AI company Anthropic, said it invested in more than 100 renewable energy projects, making it the “world’s largest corporate purchaser of renewable energy for the fourth year in a row.”

This can all feel like a bit of spin, as these tech companies move the narrative toward their use of green energy rather than questioning whether they truly need to be consuming so much energy in the first place.

That’s on the heals of OpenAI partner, Microsoft, working on getting approval for nuclear energy to help power its AI operations. Last year Amazon, which is a major investor in AI company Anthropic, said it invested in more than 100 renewable energy projects, making it the “world’s largest corporate purchaser of renewable energy for the fourth year in a row.”

This can all feel like a bit of spin, as these tech companies move the narrative toward their use of green energy rather than questioning whether they truly need to be consuming so much energy in the first place.

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What’s on your mind?

Meta is rolling out a new chatbot, Meta AI, to its 3 largest social media properties: Facebook, Instagram and WhatsApp.

On Facebook the usual search bar for some users has been replaced with “Ask Meta AI anything” — a prompt that could give millions of people their first ever interaction with an AI chatbot.

Meta has been increasingly focused on AI ever since ChatGPT exploded into the mainstream in late 2022. In earnings calls, the focus has never been clearer: Facebook execs made ~10x more references to artificial intelligence than the Metaverse, the company’s previous primary focus which prompted its rebrand in October 2021.

Metaverse mentions

Meta has been increasingly focused on AI ever since ChatGPT exploded into the mainstream in late 2022. In earnings calls, the focus has never been clearer: Facebook execs made ~10x more references to artificial intelligence than the Metaverse, the company’s previous primary focus which prompted its rebrand in October 2021.

Metaverse mentions